Valdecoxib
| Evidence Level: N/A | Predicted Indications: 0 |
Table of Contents
Valdecoxib
Quick Overview
| Item | Content |
|---|---|
| Original Indication | Not recorded in the local data |
| India Market Status | Listed in a compiled Indian medicine price dataset (at least 20) – CDSCO approval status is not included in this data |
| Number of Listed Products | at least 20 |
India Market Information
The records compiled for this report list at least 20 valid single-ingredient registrations. The list may be partial. None of the records contains approved-indication text. Five examples:
| Authorization Number | Product Name | Dosage Form | Approved Indication |
|---|---|---|---|
| 240122 | Valigud 10mg Tablet | Strip of 10 tablets | Not stated in the records |
| 237265 | Vacox 40mg Tablet | Strip of 10 tablets | Not stated in the records |
| 239198 | Valsafe 20mg Tablet | Strip of 10 tablets | Not stated in the records |
| 240499 | Valcox 40mg Injection | Vial of 5 ml injection | Not stated in the records |
| 238421 | Valcib 20mg Tablet | Strip of 10 tablets | Not stated in the records |
Safety Considerations
- Drug Interactions: 222 interactions were recorded. Most listed ones are Moderate, including corticosteroids (hydrocortisone, dexamethasone, betamethasone, budesonide, triamcinolone), acetylsalicylic acid, metformin, glimepiride, chlorpropamide, mesalazine, balsalazide, cimetidine, clarithromycin, metronidazole, vancomycin and aprepitant. Omeprazole is rated Minor.
- Regulatory history (from the literature, to be verified): Valdecoxib (Bextra) was reportedly withdrawn from the US market in 2005 because of cardiovascular risk and serious skin reactions (Stevens-Johnson syndrome, toxic epidermal necrolysis). This conflicts with the “Marketed” status in the Indian records and should be checked against the current CDSCO status.
Package insert warnings and contraindications were not available for this report. Please refer to the package insert for them.
Disclaimer
This content is for research purposes only and does not constitute medical advice. Clinical validation is required before any clinical application.