Flunarizine

Evidence Level: N/A

Predicted Indications: 0

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Table of Contents

1. Flunarizine
   1. Pharmacist Assessment Report
   2. Flunarizine: Known uses and market status in India
   3. Summary
   4. Quick overview
   5. Known uses among the model’s candidates
      1. Approved (supported by a licence or label)
      2. Related to an approved indication (same disease category)
      3. Relations recorded in the knowledge graph (no approval found)
   6. India Market Information
   7. Safety Considerations
   8. Disclaimer

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Pharmacist Assessment Report

Flunarizine: Known uses and market status in India

Summary

The TxGNN deep-learning model (score ≥ 0.99) produced candidates for Flunarizine, but every candidate that can be traced to a source is already a known use. There is therefore currently no new predicted indication for this drug. The single known use among the candidates is supported by the official label.

Quick overview

Item	Content
New predicted indications	None (all traceable model candidates are known uses)
Known uses among model candidates	1
Evidence level	Not applicable
India Market Status	Listed in a compiled Indian medicine price dataset (at least 20) – CDSCO approval status is not included in this data
Number of Listed Products	at least 20

Known uses among the model’s candidates

Approved (supported by a licence or label)

Indication	Source
migraine disorder	official label (curated); approved indication: migraine

Related to an approved indication (same disease category)

Indication	Approved category
none	none

Relations recorded in the knowledge graph (no approval found)

Indication
none

India Market Information

Licence	Product	Dosage form	Status
144126	Migrawave 5 Tablet	strip of 10 tablets	Valid
86044	Flugran 10 Tablet	strip of 10 tablets	Valid
86306	Flunarest 5mg Tablet	strip of 10 tablets	Valid
144549	Myzine 10mg Tablet	strip of 10 tablets	Valid
94615	Grain 10mg Tablet	strip of 10 tablets	Valid
86225	Fluriz 10mg Tablet	strip of 10 tablets	Valid
167609	Oxigran 5mg Tablet	strip of 10 tablets	Valid
165532	Onezine 5mg Tablet	strip of 10 tablets	Valid
86464	Fenzy 10 Tablet	strip of 10 tablets	Valid
237975	Volzine 5mg Tablet	strip of 10 tablets	Valid
88593	Flunamat 5mg Tablet	strip of 10 tablets	Valid
157543	Nomigam 10mg Tablet	strip of 10 tablets	Valid
84209	Flunarin 5 Tablet	strip of 10 tablets	Valid
91167	Flunawyn 5mg Tablet	strip of 10 tablets	Valid
244404	Xelium 5mg Tablet	strip of 10 tablets	Valid
88448	Flunahist 5mg Tablet	strip of 10 tablets	Valid
97354	Grenate 10mg Tablet	strip of 10 tablets	Valid
106344	Headzin 10 Tablet	strip of 10 tablets	Valid
138733	Migrellium 5 Tablet	strip of 10 tablets	Valid
136888	Migrazine 10mg Tablet	strip of 10 tablets	Valid

Only part of the licence list is held in the data; the list may be incomplete.

Safety Considerations

Please refer to the package insert for safety information.

Pharmacology data compiled for this report show flunarizine acts on the dopamine D2 receptor and on T-type calcium channels. No formal drug-drug interaction ratings are available. A Phase 1 study (NCT00752466) examined the pharmacokinetic interaction between flunarizine and topiramate, but its results are not summarized here.

Disclaimer

This content is for research purposes only and does not constitute medical advice. Clinical validation is required before any clinical application.

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