The TxGNN deep-learning model (score ≥ 0.99) produced candidates for Epalrestat, but every candidate that can be traced to a source is already a known use. There is therefore currently no new predicted indication for this drug. The single known use is listed below with its source.
Quick overview
Item
Content
New predicted indications
None (all traceable model candidates are known uses)
Known uses among model candidates
1
Evidence level
Not applicable
India Market Status
Listed in a compiled Indian medicine price dataset (at least 20) – CDSCO approval status is not included in this data
Number of Listed Products
at least 20
Known uses among the model’s candidates
Approved (supported by a licence or label)
Indication
Source
type 2 diabetes nephropathy
licence in another country (approved indication: diabetes)
Related to an approved indication (same disease category)
Indication
Approved category
none
none
Relations recorded in the knowledge graph (no approval found)
Indication
none
India Market Information
Licence
Product
Dosage form
Status
74029
Epstat 150mg Tablet SR
strip of 10 tablet sr
Valid
138007
Mepal 150mg/1500mcg Tablet
strip of 10 tablets
Valid
80995
Epalrest-M Tablet
strip of 10 tablets
Valid
81481
Epalpex-M SR Tablet
strip of 10 tablet sr
Valid
1404
Alrista Forte Tablet
strip of 10 tablets
Valid
72953
Epineuron SR Tablet
strip of 10 tablet sr
Valid
124764
Listap 150 SR Tablet
strip of 10 tablet sr
Valid
74234
Eparel 50 Tablet
strip of 10 tablets
Valid
155510
Nurestat 50mg Tablet
strip of 10 tablets
Valid
6866
Aristat 50mg Tablet
strip of 10 tablets
Valid
76107
Epalpex 150 SR Tablet
strip of 10 tablet sr
Valid
131645
Listap 50mg Tablet
strip of 10 tablets
Valid
802
Alrista Plus Tablet SR
strip of 10 tablet sr
Valid
74143
Epineuron Tablet
strip of 10 tablets
Valid
175127
Pre Aldonil 150mg/150mg Tablet
strip of 10 tablets
Valid
468
Aldonil Tablet
strip of 10 tablets
Valid
74687
Epo 150 Tablet SR
strip of 10 tablet sr
Valid
155602
Nurestat-Plus Tablet SR
strip of 10 tablet sr
Valid
154798
Nurestat 150SR Tablet
strip of 10 tablet sr
Valid
874
Aldonil Plus Tablet SR
strip of 10 tablet sr
Valid
Only part of the licence list is held in the data; the list may be incomplete.
Safety Considerations
Drug Interactions: One pharmacology-based interaction record was identified, with the enzyme CYP4A11 as a target of epalrestat. No severity level is assigned, and no interactions with specific co-administered drugs were identified.
For other safety information, including warnings and contraindications, please refer to the package insert.
Disclaimer
This content is for research purposes only and does not constitute medical advice.
Clinical validation is required before any clinical application.