Diltiazem

Evidence Level: N/A Predicted Indications: 0

Table of Contents

  1. Diltiazem
    1. Pharmacist Assessment Report
    2. Diltiazem: Known uses and market status in India
    3. Summary
    4. Quick overview
    5. Known uses among the model’s candidates
      1. Approved (supported by a licence or label)
      2. Related to an approved indication (same disease category)
      3. Relations recorded in the knowledge graph (no approval found)
    6. India Market Information
    7. Safety Considerations
    8. Disclaimer

Pharmacist Assessment Report

Diltiazem: Known uses and market status in India

Summary

The TxGNN model’s candidates for Diltiazem (score ≥ 0.99) are all known uses, so there is currently no new predicted indication. The one candidate that can be traced to a source is Prinzmetal angina, which is supported by a licence in another country.

Quick overview

Item Content
New predicted indications None (all traceable model candidates are known uses)
Known uses among model candidates 1
Evidence level Not applicable
India Market Status Listed in a compiled Indian medicine price dataset (at least 20) – CDSCO approval status is not included in this data
Number of Listed Products at least 20

Known uses among the model’s candidates

Approved (supported by a licence or label)

Indication Source
Prinzmetal angina licence in another country (approved indication: angina)
Indication Approved category
none none

Relations recorded in the knowledge graph (no approval found)

Indication
none

India Market Information

Licence Product Dosage form Status
64170 Dizy 10 Tablet strip of 10 tablets Valid
71240 Dilzex 30mg Tablet strip of 20 tablets Valid
183456 Q-DIL 90MG TABLET strip of 10 tablets Valid
66263 DZ CD 90mg Capsule strip of 10 capsules Valid
36631 Channel 30 Tablet MR strip of 10 tablet mr Valid
59813 Dilcontin 60 Tablet CR strip of 10 tablet cr Valid
62286 Delta 90 SR Tablet strip of 10 tablet sr Valid
77677 Eldizem 30mg Tablet strip of 10 tablets Valid
60306 DTM 90 SR Tablet strip of 10 tablet sr Valid
67328 Dilkind 90mg Tablet SR strip of 10 tablet sr Valid
166990 Orticard 60mg Tablet strip of 10 tablets Valid
112106 Ionozem CD 120mg Tablet strip of 10 tablets Valid
69353 Diltime 30mg Tablet strip of 10 tablets Valid
64863 Dilcardia 90mg Tablet SR strip of 10 tablet sr Valid
63935 DZ 60mg Tablet strip of 10 tablets Valid
37885 Channel 60mg Tablet strip of 10 tablets Valid
70909 Diltp 60mg Tablet strip of 1 Tablet Valid
68045 Dilsantin 30mg Tablet strip of 10 tablets Valid
69915 DZ CD 120mg Capsule strip of 10 capsules Valid
50618 Channel 20mg Tablet strip of 10 tablets Valid

Only part of the licence list is held in the data; the list may be incomplete.

Safety Considerations

  • Contraindications / risk conditions (knowledge-graph data, not label text): Associations include aortic stenosis, hypertrophic cardiomyopathy, hypotensive disorders, atrioventricular block, sick sinus syndrome, Wolff-Parkinson-White syndrome and Lown-Ganong-Levine syndrome, and ventricular tachycardia. Other recorded associations are kidney disease, liver disease, angioedema (including hereditary forms), neutropenia and agranulocytosis. These should be verified against the product label.
  • Drug Interactions: 369 interactions were recorded. The listed ones are mostly Moderate, including corticosteroids (hydrocortisone, dexamethasone, betamethasone, budesonide, triamcinolone), pioglitazone, bupropion, aprepitant, morphine, aspirin, canagliflozin and various calcium salts. Loperamide is a Major interaction.

Please also refer to the package insert for full warnings, as label-based safety data was not available.

Disclaimer

This content is for research purposes only and does not constitute medical advice. Clinical validation is required before any clinical application.