Brinzolamide

Evidence Level: N/A

Predicted Indications: 0

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Table of Contents

1. Brinzolamide
   1. Pharmacist Assessment Report
   2. Brinzolamide: Known uses and market status in India
   3. Summary
   4. Quick overview
   5. Known uses among the model’s candidates
      1. Approved (supported by a licence or label)
      2. Related to an approved indication (same disease category)
      3. Relations recorded in the knowledge graph (no approval found)
   6. India Market Information
   7. Safety Considerations
   8. Disclaimer

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Pharmacist Assessment Report

Brinzolamide: Known uses and market status in India

Summary

The TxGNN deep-learning model (score ≥ 0.99) produced candidates for Brinzolamide, but every candidate that can be traced to a source is already a known use. There is therefore currently no new predicted indication for this drug. The one known use found, primary hereditary glaucoma, is supported by a licence in another country.

Quick overview

Item	Content
New predicted indications	None (all traceable model candidates are known uses)
Known uses among model candidates	1
Evidence level	Not applicable
India Market Status	Listed in a compiled Indian medicine price dataset (at least 20) – CDSCO approval status is not included in this data
Number of Listed Products	at least 20

Known uses among the model’s candidates

Approved (supported by a licence or label)

Indication	Source
primary hereditary glaucoma	licence in another country (approved indication: glaucoma)

Related to an approved indication (same disease category)

Indication	Approved category
none	none

Relations recorded in the knowledge graph (no approval found)

Indication
none

India Market Information

Licence	Product	Dosage form	Status
811	Azarga Eye Drop	bottle of 5 ml Eye Drop	Valid
26679	B2 Doc Eye Drop	bottle of 5 ml Eye Drop	Valid
26342	Brinolar BKC Free Eye Drop	bottle of 5 ml Opthalmic Suspension	Valid
201460	Sentibrim-BZ Opthalmic Suspension	bottle of 5 ml Opthalmic Suspension	Valid
199916	Synca Eye Drop	bottle of 5 ml Eye Drop	Valid
59726	Duo 2 Eye Drop	bottle of 5 ml Eye Drop	Valid
26144	Brinzolast Eye Drop	bottle of 5 ml Eye Drop	Valid
26032	Brinzox-T Eye Drop	packet of 5 ml Eye Drop	Valid
123726	Lupibrin Eye Drop	bottle of 5 ml Opthalmic Suspension	Valid
25952	Brinzotim Eye Drop	packet of 5 ml Eye Drop	Valid
25930	Betafree Eye Drop	bottle of 5 ml Eye Drop	Valid
26947	Brinzemic-B Eye Drop	bottle of 5 ml Eye Drop	Valid
26865	Brinzodoc 1% Eye Drop	bottle of 5 ml Eye Drop	Valid
26360	Brinzagan Opthalmic Suspension	packet of 5 ml Opthalmic Suspension	Valid
335	Azopt Opthalmic Suspension	bottle of 5 ml Eye Drop	Valid
216795	Tregmon Eye Drop	bottle of 5 ml Eye Drop	Valid
26646	Brivizac Eye Drop	bottle of 5 ml Eye Drop	Valid
199796	Simbrinza Opthalmic Suspension	packet of 5 ml Opthalmic Suspension	Valid
25981	Brinzox Opthalmic Suspension	bottle of 5 ml Opthalmic Suspension	Valid
25935	Brivex Eye Drop	packet of 5 ml Eye Drop	Valid

Only part of the licence list is held in the data; the list may be incomplete.

Safety Considerations

• Drug Interactions: The interaction screen returned 32 potential interacting drugs. The severity level is unclassified for all of those listed, so clinical significance cannot be judged. Examples include pantoprazole, omeprazole, lansoprazole, prednisone, prednisolone, dexamethasone, triamcinolone, simvastatin, rosuvastatin, warfarin, clopidogrel, pioglitazone, potassium chloride and salbutamol.

Please refer to the package insert for warnings and contraindications.

Disclaimer

This content is for research purposes only and does not constitute medical advice. Clinical validation is required before any clinical application.

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