Betaxolol

Evidence Level: N/A Predicted Indications: 0

Table of Contents

  1. Betaxolol
    1. Pharmacist Assessment Report
    2. Betaxolol: Known uses and market status in India
    3. Summary
    4. Quick overview
    5. Known uses among the model’s candidates
      1. Approved (supported by a licence or label)
      2. Related to an approved indication (same disease category)
      3. Relations recorded in the knowledge graph (no approval found)
    6. India Market Information
    7. Safety Considerations
    8. Disclaimer

Pharmacist Assessment Report

Betaxolol: Known uses and market status in India

Summary

All candidates produced by the TxGNN model for Betaxolol (score ≥ 0.99) that can be traced to a source are already known uses. There is therefore currently no new predicted indication for this drug in India.

Quick overview

Item Content
New predicted indications None (all traceable model candidates are known uses)
Known uses among model candidates 0
Evidence level Not applicable
India Market Status Listed in a compiled Indian medicine price dataset (3 of 3) – CDSCO approval status is not included in this data
Number of Listed Products 3 (valid: 3)

Known uses among the model’s candidates

Approved (supported by a licence or label)

Indication Source
none none
Indication Approved category
none none

Relations recorded in the knowledge graph (no approval found)

Indication
none

India Market Information

Licence Product Dosage form Status
95232 Glucoptic Eye Drop packet of 5 ml Eye Drop Valid
29999 Betapress 0.5% Eye Drop packet of 5 ml Eye Drop Valid
107898 Iobet Eye Drop bottle of 5 ml Eye Drop Valid

Safety Considerations

Package insert warnings and contraindications were not available, so please refer to the package insert for those.

  • Disease contraindications flagged in the knowledge graph (these come from drug-disease relationship data, not from label text, and need verification against the label):
    • Respiratory: asthma (including intrinsic and allergic asthma), pulmonary emphysema, bronchial disease
    • Cardiac: atrioventricular block and atrioventricular dissociation, heart cancer
    • Metabolic and endocrine: diabetes mellitus, diabetic ketoacidosis, hypoglycaemia, phaeochromocytoma and other adrenal or sympathetic tumours
    • Neuromuscular: myasthenia gravis and neuromuscular junction disease
    • Organ disease: kidney disease, liver disease, gallbladder disease, pyoureter
    • Skin: psoriasis, parapsoriasis
    • Psychiatric: anxiety disorder, neurotic disorder, dysthymic disorder
    • Other tumours: duodenum cancer, small intestine cancer
  • Drug interactions: 173 interactions were recorded. Those listed in the compiled data are mostly moderate and include epinephrine, corticosteroids (hydrocortisone, dexamethasone, betamethasone, triamcinolone, budesonide), atropine and hyoscyamine, bupropion, morphine, acetohexamide, and calcium salts. Minor interactions include acetylsalicylic acid, aluminium hydroxide and attapulgite.

The doses and routes relevant to the predicted indication have not been assessed, and the ophthalmic route is the only one registered in India.

Disclaimer

This content is for research purposes only and does not constitute medical advice. Clinical validation is required before any clinical application.



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